Diabetes occurs when your body doesn’t produce enough of the hormone “insulin” or because the insulin that is produced has a reduced effect. Insulin regulates the way your body uses the food you have eaten. If you have diabetes your body cannot cope in the usual way with sugar and other carbohydrates that you eat.
Nearly one person in 25 in the UK has diabetes mellitus.
Some children have diabetes but developing diabetes is much more common later in life. Diabetes can cause complications which affect different parts of your body, including your eye. The two main types of diabetes mellitus are known as type 1 and type 2 diabetes.
This page explains how diabetes may affect your eyes. It gives information on how your eyes should be monitored, how eye conditions related to diabetes are treated and the help available for when your sight changes.
This type of diabetes commonly occurs before the age of 30 and is the result of your body producing little or no insulin. Type 1 diabetes is primarily controlled by insulin injections so it is sometimes called insulin dependent diabetes.
This type of diabetes commonly occurs after the age of 40. In this type of diabetes your body does produce some insulin, but the amount is either too little or your body is not able to use it properly. Type 2 diabetes is generally controlled by diet, exercise and/or tablets. Although some people in this group will use insulin injections type 2 diabetes is sometimes referred to as non-insulin dependent diabetes.
People from India, Pakistan, Bangladesh and Sri Lanka (South Asian communities) have a four or five times greater risk of developing diabetes than someone from a European community. Around 20–25 per cent of South Asian adults aged 50 or over in the UK develop type 2 diabetes.
At the moment the reasons why people from these communities are more at risk of type 2 diabetes aren't fully understood. There are thought to be a number of factors involved. As well as genetic make up these include diet, being overweight and not doing enough exercise.
People from South Asian communities can also have problems using the insulin their bodies produce, making it more difficult for them to regulate the sugar in their blood. It also appears that they are more likely to put on weight around their middles, known as central obesity. This can put stress on the parts of the body that produce insulin meaning it isn't able to work properly.
If you are from a South Asian community it is important that you know about the risk of developing type 2 diabetes, the sight loss it can cause, and the steps you can take to reduce the risk of losing your sight. You will find lots of information on the Diabetes UK website about this,
GDM is a type of diabetes that sometimes arises during the second or third trimester of pregnancy. For most women this diabetes goes away after pregnancy but it increases the chances of developing type 1 or type 2 diabetes in later life.
When you look at something, light passes through the front of your eye and is focused by the cornea and lens onto your retina. The retina is a delicate tissue that is sensitive to light. It converts the light into electrical signals that travel along the optic nerve to your brain. The brain interprets these signals to “see” the world around you.
The retina is supplied with blood by a delicate network of blood vessels. These blood vessels can be damaged by diabetes.
Light entering your eye is focused onto a tiny area of your central retina called the macula. This highly specialised area of your retina is about the size of a pinhead. It is vital because it allows you to see fine detail for activities such as reading and writing, and recognising colours. The rest of your retina, called the peripheral retina, gives you side vision (or peripheral vision).
Your eye is filled with a clear jelly-like substance called the vitreous gel. Light passes through the gel to focus on the macula.
Diabetes can affect your eye in a number of ways:
Not everyone who has diabetes develops an eye complication. Of those that do, many people have a very mild form of retinopathy which may never progress to a sight-threatening condition.
The most serious complication of diabetes for your eye is the development of diabetic retinopathy. Diabetes affects the tiny blood vessels of your eye and if they become blocked or leak then the retina, and possibly your vision, will be affected. The extent of these changes determines what type of diabetic retinopathy you have. Forty per cent of people with type 1 diabetes and 20 per cent with type 2 diabetes will develop some sort of diabetic retinopathy.
This is the most common type of diabetic retinopathy and many people who have had diabetes for some time will have this early type.
The blood vessels in the retina are only very mildly affected, they may bulge slightly (microaneurysm) and may leak blood (haemorrhages) or fluid (exudates). As long as the macula is not affected, vision is normal and you will not be aware that anything is wrong. Your retinal screening test will keep a close check on these early changes and ensure that any signs of progression to more serious stages of retinopathy are detected early.
If diabetic retinopathy progresses, it can cause the blood vessels in the retina to become blocked. These blockages, when affecting a significant part of the retina, can result in areas of the retina becoming starved of oxygen. This is called ischaemia. If this happens your eye is stimulated into growing new vessels, a process called neo-vascularisation. This is the proliferative stage of diabetic retinopathy and is nature’s way of trying to repair the damage by growing a new blood supply to the oxygen starved area of your retina.
Unfortunately, these new blood vessels are weak, and grow in the wrong place – on the surface of the retina and into your vitreous gel. As a result, these blood vessels can bleed very easily which may result in large haemorrhages over the surface of the retina or into the vitreous gel. These types of haemorrhages can totally obscure the vision in the affected eye as light is blocked by the bleed and the blood in the vitreous gel. For many people, with time, the blood can be reabsorbed and their vision can improve. But for others these haemorrhages may keep happening and the blood may not fully reabsorb. This can lead to more permanent loss of sight.
Extensive haemorrhages can lead to scar tissue forming which pulls and distorts the retina. This type of advanced diabetic eye disease can result in the retina becoming detached with the risk of serious sight loss.
Only between 5 and 10 per cent of all people with diabetes develop proliferative retinopathy. It is more common in people with type 1 diabetes than type 2. Sixty per cent of type 1 diabetics show some signs of proliferative disease after having diabetes for 30 years.
Diabetic maculopathy means that your macula is affected by your diabetes. This may occur either with background, or proliferative retinopathy. If this happens, your central vision will be affected and you may find it difficult to see detail such as recognising people’s faces or seeing small print clearly. The amount of central vision that is lost varies from person to person. However, the vision that allows you to get around at home and outside (peripheral vision) is not affected.
Some people develop a type of maculopathy called diabetic macular oedema. This causes fluid to collect in your macula which can cause further problems with your central vision.
Most diabetic maculopathy can be treated with a laser, and more recently injections. These treatments aim to stop your sight getting worse, although some people may notice an improvement in their vision.
Risk factors for developing diabetic retinopathy can be divided into those you are able to control and those you cannot. Good diabetic control significantly lowers your risk of retinopathy.
You can reduce your risk of developing retinopathy or help to stop it from getting worse by:
Risk factors that cannot be controlled:
If you have diabetes and plan to have a child, your GP will discuss with you how to manage the pregnancy. Retinal screening is carried out more often during pregnancy and for a while after you have had your baby. Similarly if you develop gestational diabetes during pregnancy, you will also have more regular retinal screening during pregnancy and after your baby is born.
If you have diabetes this does not necessarily mean that your sight will be affected. If your diabetes is well controlled you are less likely to have problems, or they may be less serious. However, if there are complications that affect your eyes, this can sometimes result in serious loss of sight.
Most of the complications that diabetes causes in the eye can be treated, but it is vital that they are diagnosed early. They can only be detected by a detailed examination of your eye carried out at a specialist screening centre. If you have diabetes your GP or hospital clinic should arrange for you to have annual retinal screening. At this appointment you will have eye drops put into your eyes which dilate the pupil and allow the specialist a good view of the retina. A picture is taken using a digital retinal camera and this is looked at in detail to see if there are any changes caused by diabetes.
As you may not be aware that there is anything wrong with your eyes until it is too late, having this regular test is essential. Research shows that if retinopathy is identified early, through retinal screening, and treated appropriately, blindness can be prevented in 90 per cent of those at risk. If you have not had this type of test, ask your GP or diabetic clinic as soon as possible.
You should also go for an annual eye examination with the optometrist (optician). Your retinal screening test does not replace your regular eye examination with your optometrist.
Some optometrists will take a photograph of the back of your eye as part of your regular eye examination. This photograph does not replace your retinal screening appointment. It is very important to attend both your retinal screening appointment and your regular eye examination with the optician.
Most sight-threatening problems caused by diabetic retinopathy can be managed by laser treatment if detected early enough. The aim of laser treatment is to prevent bleeding or to prevent the growth of new blood vessels. The laser can be used in two ways:
When individual vessels or small groups of vessels are leaking, the laser can seal them. This stops the bleeding and helps reduce the swelling of your retina. This type of treatment is quick, sometimes taking only a few minutes. Localised laser treatment is used when maculopathy has been detected. Your vision is not usually affected by this type of treatment because only a very localised area of your retina is treated.
If new vessel growth (neo-vascularisation) has been detected you may need more extensive laser treatment. The aim is to treat large areas of the peripheral retina with the laser. This treatment stops your retina from producing the growth factors that stimulate new blood vessels to grow. If the treatment is successful, the new vessels shrink and disappear over a few months.
Because large areas of the peripheral retina are lasered, the effects on your vision may be significant. It is quite common to permanently lose some vision to the sides (peripheral vision) and this may affect your ability to drive safely. Night and colour vision may also be affected.
When new vessels are first detected your vision may be very good and you may not have noticed any changes to the way you see. This is because, in the initial stages, new vessels have very little effect on your vision. After the treatment your vision may be very different, for example your peripheral vision may be quite poor. You may feel that the laser has made your sight much worse. The difficult issue is, that if left untreated, the new vessels will soon bleed and cause serious loss of vision. The laser treatment is the best option for preventing this.
It is important to remember that laser treatment aims to prevent your vision from getting worse. It cannot make your vision better.
You can usually be treated in an outpatient clinic and do not normally need to stay in hospital. Eye drops enlarge your pupils so that your eye specialist can look into your eye.
Your eye is then numbed with drops and a small contact lens is put onto your eye to stop it blinking. During the treatment you will be asked to move your eyes in certain directions and you will be able to do this easily with the contact lens in place. When treatment is first suggested, ask how long each session is likely to last. Some people need more than one treatment session.
Local treatment for sealing blood vessels does not usually cause discomfort. Pan-retinal treatment can be uncomfortable, so you may need a pain-relieving tablet at the same time as your eye drops. Further pain relief is available so remember:
No treatment is possible without some side effects, but the risks to your vision of laser treatment are far fewer than the risks of not having laser treatment.
The short-term effects of the laser treatment are due to the brightness of the laser used. It can cause a temporary reduction of sight which may last an hour or two after the treatment. You may also lose a little central vision which may improve with time or notice the after effects of the laser as small black spots in your vision.
The local treatment has little long-term effect, as it only treats a very small area of your retina.
The more extensive pan-retinal treatment can have more lasting effects on your vision:
The possible side effects of treatment depend on your eye condition and the type of treatment that your specialist suggests. Ask the specialist to talk you through what they plan to do, the advantages and disadvantages of the treatment and the possible side effects, temporary or permanent, for your vision.
If you drive and have had laser treatment in both eyes or your one remaining eye you must inform the Driver and Vehicle Licensing Agency (DVLA). They may ask that you have a detailed eye examination to make sure your central and peripheral vision are good enough for safe driving.
After lengthy treatment, most people develop a headache so a headache tablet can be taken for this.
However, if the pain is severe, or if your eyesight gets worse, you should contact your eye specialist immediately. If this is not possible, go straight to the Accident and Emergency department at your nearest hospital.
Although your vision may be good, changes can be taking place in your retina that need treatment. Most sight loss due to diabetes is preventable if treatment is given early. The earlier the treatment is given the more effective it is.
The importance of early treatment of diabetic retinopathy cannot be stressed enough.
Remember, however, that if your vision is getting worse, this does not necessarily mean you have diabetic retinopathy. It may simply be a problem that can be corrected with glasses. So check it out.
Diabetes can cause macular oedema. The macula is a tiny part of the retina at the back of your eye. Diabetes can cause a build up of fluid to collect on or under your macula which leads to macular swelling, medically known as “oedema”. Diabetic macular oedema may make your central vision distorted or blurry and, over a period of time, it may cause a blank patch in the centre of your vision. When the macular oedema does not involve the centre of the macula (called fovea), laser treatment can reduce the leakage and prevent any more blurring. However, when the oedema affects the centre, then laser treatment offers no benefit.
Diabetic macular oedema, which affects the centre of the macula, can be treated with an injection rather than laser surgery. Lucentis, an anti-vascular endothelial growth factor (anti-VEGF) treatment, is licensed for use to help control the swelling. Research has shown that Lucentis can reduce the swelling and macular thickness caused by diabetic macular oedema, and reduces the blurred central vision.
Anti-VEGF medications work by blocking the effects of a growth factor (VEGF) that blood vessels need in order to form and keep leaking. The anti-VEGF drugs stop the growth of new blood vessels and can help to reduce macula oedema.
Lucentis is given by an injection into the white of your eye and you may have to have more than one injection over a period of months to get the best effect. There are restrictions on the use of Lucentis for diabetic macular oedema, which means your treatment may depend on how badly your macula is affected by swelling. Your ophthalmologist will be able to tell you whether your macular oedema can be treated by injection on the NHS.
If your eye condition becomes more severe and the gel inside your eye becomes cloudy due to haemorrhages, or if scar tissue forms causing retinal detachment, it may be necessary for you to have an operation called a vitrectomy. This procedure involves the vitreous gel being removed and replaced with a clear solution that light can pass through more easily.
When you have a vitreous or retinal haemorrhage the reduction in your vision can happen quickly and be dramatic. It can then seem frustrating that the specialist can advise waiting for up to six months before carrying out a vitrectomy. The waiting period enables your specialist to monitor how the bleed changes, to see if there are any new bleeds and more positively to see whether the bleed begins to be reabsorbed and if this results in your vision improving. The specialist will carry out the vitrectomy at the time most likely to give the best result.
A vitrectomy is a specialised and complicated operation and you need to discuss with your specialist the advantages and disadvantages of the procedure for your vision.
The changes in blood sugar levels resulting from diabetes can affect the lens inside your eye, especially when diabetes is uncontrolled. This can result in blurring of vision which comes and goes across the day. This blurring may be one of the first symptoms of diabetes although it may also occur at any time when your diabetes is not well controlled. Once your diabetes is controlled most people find this variable blurring goes away.
A cataract is a clouding of the lens of your eye, which causes the vision to become blurred or dim because light cannot pass easily to the back of your eye. This is a very common eye condition that often develops as we get older, but people with diabetes sometimes develop cataracts at an earlier age. An operation can remove the cloudy lens, which is usually replaced by a plastic lens, helping your eye to focus properly again. Your eye clinic will monitor a cataract if it is forming as part of your regular check up. Visit our Cataracts page if you would like more information.
Home testing your blood sugar levels is a very effective way of making sure you are controlling your blood glucose. You prick the side of a finger and place a drop of blood on a testing strip. You put the strip in a glucose meter which displays your blood glucose level on a screen.
If you have a sight problem you might find some meters difficult to read. However, you can now get easy-to-see meters and talking meters. Up-to-date details of meters are on the Diabetes UK website or you can call the Diabetes UK Careline on 0345 123 2399, Monday–Friday, 9am-7pm.
If you are having difficulties reading your meter at home tell someone involved with your diabetic care. You need to be able to carry out testing at home accurately and your diabetic nurse needs to work with you to ensure that you can use the meter you have chosen effectively.
Much can be done to help you use your remaining vision.
You should ask your eye specialist or optometrist about low vision aids. Alternatively, you can contact our Helpline on 0303 123 9999 or visit our Everyday living pages for more information about low vision.
If your vision is impaired, it is also worth asking your specialist to help you register as “sight impaired” (partially sighted) or “severely sight impaired” (blind). This opens the door to expert help and some financial concessions.
Being diagnosed with an eye condition can be very upsetting. You may find that you are worried about the future and how you will manage with a change in your vision. All these feelings are natural. Some people may want to talk over some of these feelings with someone outside their circle of friends or family. RNIB can help with our telephone Helpline and emotional support service. Your GP or social worker may also be able to find a counsellor for you, if you think this would help.
Royal National Institute of Blind People
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Diabetes UK Careline: 0345 123 2399
Diabetes UK website
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This webpage has been produced jointly by the Royal College of Ophthalmologists and Royal National Institute of Blind People, a certified member of the Information Standard.
© RNIB and RCOphth December 2014
© RNIB and RCOphth
Eye Health Information Disclaimer
This information has been produced jointly by the Royal College of Ophthalmologists and Royal National Institute of Blind People, a certified member of the Information Standard.
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