Title: Diabetic eye disease: A UK Incidence and Prevalence Study, Author: Rohini Mathur et al. (London School of Hygiene and Tropical Medicine), Publisher: RNIB, Year of Publication: 2017
This research report investigates trends in prevalence and incidence of diabetic retinopathy in the UK.
Diabetic retinopathy is one of the leading causes of visual impairment and blindness in the UK, particularly among working age people. In the UK, within 20 years of diagnosis, nearly all people with Type 1 and almost two thirds of people with Type 2 diabetes have some degree of retinopathy. Prior to this research, there were no UK-wide population-based measures of incidence and prevalence.
To enhance our understanding of diabetic retinopathy in the UK, RNIB commissioned the London School of Hygiene and Tropical Medicine to estimate the incidence and prevalence of diabetic retinopathy.
The aims of the research were to analyse a large patient database with millions of records and ascertain:
RNIB Data Analyst Emma Edwards discusses the findings and implications of new research into the population living with diabetic retinopathy in our latest Expert series blog.
Results from the study have been published as an article in the peer reviewed British Medical Journal.
There are a number of slight differences between this report and the British Medical Journal paper ‘Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004–2014’.
These differences are as follows:
1. The report includes information on the crude incidence and prevalence of diabetic retinopathy in key population subgroups. The paper presents age-standardized incidence and prevalences. These figures are standardized against the mid-2014 UK population estimates from the Office for National Statistics - and thus take account for the age structure of the UK population (Figure 1 and table 2 in the paper).
2. Severe diabetic retinopathy in the report includes codes for severe pre-proliferative retinopathy. In the paper, severe retinopathy is defined as proliferative retinopathy - and thus the severe DR population is slightly smaller in the paper compared to the report.
3. Risk of developing retinopathy is presented as crude hazard ratios in the report- stratified by gender, age, ethnic group, calendar year, geographical region, and deprivation. (Tables 13 and 14). In the paper, the risk of developing retinopathy is presented as an adjusted hazard ratio, which takes account of age, gender, ethnic group, deprivation, geographic region, and additionally, duration of diabetes) This is figure 2 in the paper.